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THIS CONTENT IS FOR HEALTHCARE PROFESSIONALS ONLY

Heart Failure Management Hub

This Heart Failure Management Hub provides a range of valuable educational assets to facilitate the use of SGLT-2 inhibitors and other guideline directed medical therapies as foundational treatment for heart failure (HF).

Supported by an unrestricted educational grant from AstraZeneca.

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CME Courses

(4 contents)

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CME Courses

The Advancing Management of Transthyretin Amyloidosis: A Practical Guide

author

Julian Gillmore, Martha Grogan, Laura Obici, Arnt Kristen

Published: 16/10/2023

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CME Courses

Examining a Complex Heart Failure Case

author

Andrew JS Coats, Katherine Tuttle, Richard Hobbs, Silvio Inzucchi

Published: 10/03/2023

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CME Courses

Incorporating GDMT and PRO Endpoints for Personalised Heart Failure Management

author

Andrew JS Coats, Mikhail Kosiborod, Shelley Zieroth, Biykem Bozkurt, Giuseppe Rosano

Published: 23/03/2023

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CME Courses

SGLT-2 Inhibitors - Another Piece of the Puzzle in Heart Failure

author

Scott Solomon, John JV McMurray, Carolyn Lam, Muthiah Vaduganathan

Published: 08/09/2022

Videos

(18 contents)

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Videos

What is GDMT?

EN

author

Andrew JS Coats, Mikhail Kosiborod

Prof Coats and Dr Kosiborod summarise foundational guideline-directed medical therapy (GDMT) across the spectrum of heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF).

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Early Initiation and Better Clinical Outcomes

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author

Andrew JS Coats, Mikhail Kosiborod

Prof Coats and Dr Kosiborod discuss the relationship between early initiation of foundational GDMT and better clinical outcomes by exploring recent clinical trial data from STRONG-HF.

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Achieving Early Uptake of GDMT

EN

author

Andrew JS Coats, Mikhail Kosiborod

Prof Coats and Dr Kosiborod cover practical approaches for ensuring early optimal GDMT in heart failure, such as, the use of electronic health records and protocols for specific patient subgroups.

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Videos

Initiating SGLT-2 Inhibitors

EN

author

Biykem Bozkurt, Giuseppe Rosano

Prof Rosano and Dr Bozkurt examine recent guidelines and consider best practice for initiating SGLT-2 inhibitors across the continuum of HF and in patients already on HF medication versus those who are treatment-naïve.

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Evolving the Management Approach - AEs and MDTs

EN

author

Biykem Bozkurt, Giuseppe Rosano

Prof Rosano and Dr Bozkurt discuss the practicalities of continual management of HF patients on an SGLT-2 inhibitor and how the broader multidisciplinary team should be aware of the benefits of early SGLT-2 initiation in HF.

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QoL and Functional Measures of Treatment Success

EN

author

Shelley Zieroth, Mikhail Kosiborod

Dr Kosiborod and Dr Zieroth discuss QoL and functional status as tangible measurements of treatment success.

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Clinical Evidence

EN

author

Mikhail Kosiborod, Shelley Zieroth

Dr Kosiborod and Dr Zieroth look at the relationship between initiating GDMT and QoL / functional status improvement. They discuss some of the specific clinical trial data showing how initiating SGLT-2 inhibitors improves QoL and functional outcomes.

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Practically Implementing PROMs

EN

author

Shelley Zieroth, Mikhail Kosiborod

Dr Kosiborod and Dr Zieroth discuss practical implication of patient reported outcome measures (PROMs).

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Implementation Strategies for GDMT in Respect of the New Guidelines

EN

author

Mikhail Kosiborod, Harriette Van Spall

In this short interview, Dr Kosiborod and Dr Van Spall summarise some of the key changes in guidance following the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

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The DELIVER Trial in Brief

EN

author

Carolyn Lam, John JV McMurray

Prof Lam discusses DELIVER with one of the trial’s lead investigators, Prof McMurray. As well as the key results from DELIVER, they consider how to apply them to HFpEF patients in the real-world.

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DELIVER and DAPA-HF Pooled Analysis in Brief

EN

author

Carolyn Lam, John JV McMurray

Prof Lam and Prof McMurray put into context the pooled analysis of DELIVER and DAPA-HF and consider whether these results can be extrapolated to the entire HF population, addressing the suitability of patients according to their individual EF.

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Guideline Directed Medical Therapy in HF

EN

author

Giuseppe Rosano, Biykem Bozkurt

In this short peer-to-peer discussion, Dr Biykem Bozkurt, and Prof Giuseppe Rosano, discuss the main updates from the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

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Videos

SGLT-2 Inhibitors Across the Range Of EF

EN

author

Giuseppe Rosano, Mikhail Kosiborod

In this short peer-to-peer discussion, Prof Giuseppe Rosano and Dr Mikhail Kosiborod, discuss the main updates from the 2022 AHA/ACC/HFSA Guideline for the Management of Heart Failure.

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Re-Evaluating GDMT in Heart Failure: Part 1 - Accommodating New Evidence in HF Guidelines

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author

Biykem Bozkurt, Gianluigi Savarese

Dr Savarese and Dr Bozkurt summarise the 2022 American guidelines new recommendations for pharmacological agents in HF and the evidence that was unavailable in the 2021 European guidelines.

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Re-Evaluating GDMT in Heart Failure: Part 2 - Current Trends in HF GDMT

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author

Orly Vardeny, Gianluigi Savarese

Dr Savarese and Dr Vardeny discuss the recent guideline recommendations for four pillar GDMT and how well these are being utilised in clinical practice for patients with HF.

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HF Guideline Review Part 1: Distilling the New ESC Guideline Update

EN

author

Carolyn Lam, Giuseppe Rosano

Prof Lam and Prof Rosano discuss why there was a need for an update of the 2021 guidelines, and consider the changing landscape following several randomised controlled trials.

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HF Guideline Review Part 2: Assessing the Impact on Practice

EN

author

Carolyn Lam, Giuseppe Rosano

Prof Lam and Prof Rosano consider the recommendations for SGLT2 inhibitor use, to reduce cardiovascular death and heart failure hospitalisation, and the expected impact on clinical practice.

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HF Guideline Review Part 3: The Future of Heart Failure Management

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author

Carolyn Lam, Giuseppe Rosano

Prof Lam and Prof Rosano discuss the power of early detection in improving outcomes and stress the need for accessible and efficient diagnostic testing for the prevention of heart failure among high-risk patients.

Heart Failure in Focus Podcast

(8 contents)

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Episode 8: Making Progress in HFpEF

Podcasts

Episode 8: Making Progress in HFpEF

EN

author

Muthiah Vaduganathan, Giuseppe Rosano

Dr Muthiah Vaduganathan is joined by Prof Giuseppe Rosano who played a central part in the development of the 2023 European heart failure guideline focussed update and an earlier publication on HFpEF phenotyping.

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Episode 7: The Evolving Role of Primary Care in HF

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Muthiah Vaduganathan, Xavier Cos

Dr Muthiah Vaduganathan is joined by Prof Xavier Cos, a general practitioner and Chairman of Primary Care Diabetes Europe, to discuss the current and future role of primary care in heart failure (HF).

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Episode 6: Cardiorenal Care in Practice
20:40

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Episode 6: Cardiorenal Care in Practice

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author

Muthiah Vaduganathan

Dr Muthiah Vaduganathan speaks with Dr Kieran McCafferty, Consultant Nephrologist at Barts NHS Health Trust London, about the growing need for effective management strategies in cardiorenal disease.

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Episode 5
23:06

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Episode 5: Functional & QoL Outcomes in a Sea of Clinical Event Data

EN

author

Muthiah Vaduganathan, Mikhail Kosiborod

Dr Vaduganathan is joined by Dr Mikhail Kosiborod, leading expert on Quality of Life (QoL) instruments world-wide, to discuss functional and QoL outcomes of foundational therapies in Heart Failure (HF) and the clinical application of this data.

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Episode 4: Mitigating Clinical Inertia in Heart Failure

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author

Muthiah Vaduganathan, Tariq Ahmad

Dr Vaduganathan is joined by Dr Tariq Ahmad to discuss the reality of sub-optimal treatment and possible ways forward using behavioural “nudges” embedded within electronic health records.

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21:04

Podcasts

Episode 3: 4 Onboard: Implementing GDMT

EN

author

Muthiah Vaduganathan, Biykem Bozkurt

Dr Vaduganathan is joined by Dr Biykem Bozkurt, for the third episode, to discuss some of the most challenging questions around implementing guideline directed medical therapy (GDMT).

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Episode 2: Your Questions Answered
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Episode 2: Your Questions Answered

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author

Muthiah Vaduganathan, Carolyn Lam

Dr Vaduganathan is joined by Prof Carolyn Lam to continue the theme of SGLT-2 inhibitors in heart failure. Listen to them answer your questions about SGLT-2 inhibitors and the practical management of heart failure patients.

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Episode 1: Emerging Data from the ESC
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Episode 1: Emerging Data from the ESC

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author

Muthiah Vaduganathan, Scott Solomon

Dr Muthiah Vaduganathan is joined by Prof Scott Solomon for the first episode in this new series, Heart Failure in Focus, to discuss the DELIVER data which was released at the ESC Congress 2022 in Barcelona.

Complex Patients

(9 contents)

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Complex Patients

Examining a Complex Heart Failure Case: Part 1 - Approaching the Patient

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author

Andrew JS Coats, Richard Hobbs, Katherine Tuttle, Silvio Inzucchi

The multidisciplinary panel discuss their initial approach to a patient from the perspective of their different backgrounds and how they can most effectively manage this patient as a team.

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Complex Patients

Examining a Complex Heart Failure Case: Part 2 - Diagnosing the Patient

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author

Silvio Inzucchi, Richard Hobbs, Katherine Tuttle, Andrew JS Coats

The panel discuss labelling the patient with a diagnosis, prioritising problems for management and ask who should start foundational therapy of SGLT-2 inhibitors. 

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Complex Patients

Examining a Complex Heart Failure Case: Part 3 - Managing the Patient

EN

author

Andrew JS Coats, Silvio Inzucchi, Richard Hobbs, Katherine Tuttle

The panel review poll results from the audience on approach to management, discuss their approach to initiating GDMT and explore overcoming a dip in renal function following SGLT-2 inhibition.  

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Complex Patients

Examining a Complex Heart Failure Case: Part 4 - Follow-up & Referral

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author

Katherine Tuttle, Andrew JS Coats, Richard Hobbs, Silvio Inzucchi

The panel now discuss the ongoing patient centred care required for this patient, continued investigation and holistic co-management.  

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Complex Patients

Examining a Complex Heart Failure Case: Part 5 - Responding to a Changing Patient

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author

Richard Hobbs, Silvio Inzucchi, Katherine Tuttle, Andrew JS Coats

The panel discuss how they would continue to manage the patient with foundational therapy as their symptoms, disease severity and comorbidities change over time.

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Complex Patients

Examining a Complex Heart Failure Case: Part 6 - Re-cap and Summary

EN

author

Andrew JS Coats

Prof Coats closes this programme by summarising key learning points from this complex case of HFpEF.

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Complex Patients

Ejection Fraction - How Important Is It Today?

EN

author

Martin R Cowie, Richard Hobbs, Kieran Docherty, Bharathi Upadhya

During the first part of this roundtable, chaired by Prof Cowie, our multidisciplinary panel discuss the importance of EF, and analyse survey data.

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Complex Patients

HFrEF and HFpEF Case Review

EN

author

Martin R Cowie, Richard Hobbs, Kieran Docherty, Bharathi Upadhya

During the second part of this roundtable, our multidisciplinary panel discuss two patient cases and their treatment strategies based on recent guidelines and data updates.

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The Expanding Role of Primary Care in Ongoing HF Management

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author

Richard Hobbs, Martin R Cowie, Kieran Docherty, Bharathi Upadhya

During the final part of this roundtable, the panel discuss the role of primary care in ongoing heart failure management.

HFA 2024

(7 contents)

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Management Observations From Real-World Data

HFA 2024

Management Observations From Real-World Data

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author

Lisa Anderson, Giuseppe Rosano, Antoni Bayés-Genís

Part one of this exclusive discussion 'Reshaping Early Identification and Diagnosis of Heart Failure' recorded live from HFA 2024.

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HFA 2024

What Are We Learning From Diagnostic Practices?

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author

Antoni Bayés-Genís, Giuseppe Rosano, Lisa Anderson

Part two of this exclusive discussion 'Reshaping Early Identification and Diagnosis of Heart Failure' recorded live from HFA 2024.

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HFA 2024

Practical Implementation of Real-World Data

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Giuseppe Rosano, Antoni Bayés-Genís, Lisa Anderson

Part three of this exclusive discussion 'Reshaping Early Identification and Diagnosis of Heart Failure' recorded live from HFA 2024.

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HFA 2024

Part 1: Implementing GDMT: What Should We Be Doing?

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author

Antoni Bayés-Genís

Part one of 'A Race Against Time: Accelerating the Adoption of GDMT in Heart Failure', Prof Bayés-Genís presents and explores the best practices and strategies for implementing GDMT in clinical settings.

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HFA 2024

Part 2: Implementing GDMT: What Is Really Happening?

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author

Lisa Anderson

Part two of 'A Race Against Time: Accelerating the Adoption of GDMT in Heart Failure', Dr Anderson follows up on Prof Bayés-Genís' presentation by highlighting current real-world practices.

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HFA 2024

Part 3: The Implication of Delayed Diagnosis and Sub-Optimal GDMT

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author

Stephen J Greene

Part three of 'A Race Against Time: Accelerating the Adoption of GDMT in Heart Failure', Dr Greene examines and highlights the consequences of delayed diagnosis and sub-optimal implementation of GDMT on patient outcomes.

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HFA 2024

Part 4: Panel Discussion & Audience Q&A

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author

Antoni Bayés-Genís, Lisa Anderson, Stephen J Greene

The panel further explore the topic, providing insights into the challenges related to delays and adoption rates in both community and hospital settings, and the significant impact on patient care.

ESC 2023

(10 contents)

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Introduction and Part 1: Addressing New Guidelines

ESC 2023

Introduction and Part 1: Addressing New Guidelines

EN

author

Carolyn Lam, Stephen J Greene, Mark Petrie, Gianluigi Savarese

Part one of 'Implementing Heart Failure Guidelines with Collaborative Care', this symposium provides an update on the latest guideline recommendations in HFpEF and how to implement them effectively in clinical practice.

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Part 2: Patient Vignette

ESC 2023

Part 2: Patient Vignette

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author

Carolyn Lam

Part two of 'Implementing Heart Failure Guidelines with Collaborative Care', this session presents a newly diagnosed HFpEF patient and demonstrates barriers to GDMT.

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Part 3: Early / Rapid Initiation of GDMT

ESC 2023

Part 3: Early / Rapid Initiation of GDMT

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author

Carolyn Lam, Stephen J Greene, Mark Petrie, Gianluigi Savarese

Part three of 'Implementing Heart Failure Guidelines with Collaborative Care', the panel discuss latest guideline recommendations in HFpEF and how to implement them effectively in clinical practice.

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ESC 2023

Part 4: Anticipating Barriers in HFpEF

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author

Carolyn Lam, Stephen J Greene, Mark Petrie, Gianluigi Savarese

Part four of 'Implementing Heart Failure Guidelines with Collaborative Care', the panel provide valuable insights into the challenges and barriers faced while adopting new guideline-directed medical therapy for heart failure patients.

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Part 5: The Heart Failure Team

ESC 2023

Part 5: The Heart Failure Team

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author

Carolyn Lam, Stephen J Greene, Mark Petrie, Gianluigi Savarese

Part five of 'Implementing Heart Failure Guidelines with Collaborative Care', this session emphasises the significance of cross-functional teams in managing heart failure therapy.

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Part 6: Audience Q&A and Panel Discussion

ESC 2023

Part 6: Audience Q&A and Panel Discussion

EN

author

Carolyn Lam

Part six of 'Implementing Heart Failure Guidelines with Collaborative Care', this session closes with audience Q&A and panel discussion.

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Part 1: ATTR – A Multi-system Disease Posing Unique Challenges

ESC 2023

Part 1: ATTR – A Multi-system Disease Posing Unique Challenges

EN

author

Julian Gillmore, Laura Obici, Martha Grogan, Arnt Kristen

Part one of 'The Advancing Management of Transthyretin Amyloidosis: A practical Guide', this symposium provides you with the practical knowledge and tools to implement ATTR-cm effectively in your clinical practice.

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Assessing Cardiac Manifestations of ATTR

ESC 2023

Part 2: Assessing Cardiac Manifestations of ATTR

EN

author

Martha Grogan

Part two of 'The Advancing Management of Transthyretin Amyloidosis: A practical Guide', Dr Grogan uses a patient journey to discuss the cardiac implications of ATTR and the diagnosis and monitoring of symptomatic cases with ATTR-cm.

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Part 3: Long-term Management

ESC 2023

Part 3: Long-term Management

EN

author

Laura Obici

Part three of 'The Advancing Management of Transthyretin Amyloidosis: A practical Guide', Dr Obici focuses on tracking disease progression by evaluating multiple symptoms and their assessment frequency, involving various healthcare professionals.

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Part 4: What’s in our Future Toolbox?

ESC 2023

Part 4: What’s in our Future Toolbox?

EN

author

Arnt Kristen

Part four of 'The Advancing Management of Transthyretin Amyloidosis: A practical Guide', Prof Kristen delves into the realm of innovative pharmacological management.

HFA 2023

(3 contents)

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HFA 2023

The Urgency to Implement GDMT

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author

Gianluigi Savarese, Stephen J Greene, Mark Petrie

In this first session of this symposium entitled 'Overcoming the Challenges in Optimising GDMT in HF', the panel delve into the urgency of implementing GDMT for patients with heart failure.

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HFA 2023

Barriers to Achieving Optimal Medical Therapy

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author

Gianluigi Savarese, Stephen J Greene, Mark Petrie

In the second session, the panel engage in a thought-provoking discussion about the barriers that impede the achievement of optimal medical therapy.

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HFA 2023

Practical Strategies to Implement New Algorithms in GDMT

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author

Gianluigi Savarese, Stephen J Greene, Mark Petrie

In the final session, the panel aims to equip attendees with practical strategies to navigate the complexities of implementing new algorithms in GDMT and improving patient care.

ESC 2022

(4 contents)

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ESC 2022

SGLT2 Inhibitors: Light at the End of the Tunnel

EN

author

Scott Solomon

Presented, and recorded, at ESC Congress 2022 in Barcelona, our globally-renowned faculty explain how to assess the latest data for SGLT2 inhibitors in heart failure (HF) and how to apply it in real-world practice. 

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ESC 2022

SGLT2 Inhibitors Across the Spectrum of Heart Failure

EN

author

John JV McMurray

Presented, and recorded, at ESC Congress 2022 in Barcelona, our globally-renowned faculty explain how to assess the latest data for SGLT2 inhibitors in heart failure (HF) and how to apply it in real-world practice. 

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ESC 2022

Practical Considerations for Treating HF With Mildly Reduced and Preserved EP

EN

author

Carolyn Lam

Presented, and recorded, at ESC Congress 2022 in Barcelona, our globally-renowned faculty explain how to assess the latest data for SGLT2 inhibitors in heart failure (HF) and how to apply it in real-world practice. 

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ESC 2022

Implementing Best Practices Across the Spectrum of Heart Failure

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author

Muthiah Vaduganathan

Presented, and recorded, at ESC Congress 2022 in Barcelona, our globally-renowned faculty explain how to assess the latest data for SGLT2 inhibitors in heart failure (HF) and how to apply it in real-world practice.