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Advancements in Triglyceride-lowering Therapies: Insights from ESC 2024

Topic:
  • Prevention

Available Credit:

  • 1.00 EBAC

Course Published On:

Course Expiry Date:

Advancements in Triglyceride-lowering Therapies: Insights from ESC 2024
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Overview

In this course, recorded at ESC 2024 in London, Prof Gerald Watts (University of Western Australia, Perth, Australia) is joined by Prof Robert S Rosenson (Mount Sinai Icahn School of Medicine, New York, US) to discuss developments in triglyceride-lowering therapies.

 

The faculty consider triglycerides as a risk factor for cardiovascular disease and explore the relationship between triglycerides and the risk of acute pancreatitis and ASCVD. In addition, the series covers familial chylomicronemia syndrome (FCS), including the role of genetic testing to identify patients through risk assessment.

 

The faculty also review PALISADE, a phase 3 trial of investigational plozasiran in patients with diagnosed FCS, that concluded that patients with persistent chylomicronemia who received plozasiran had significantly lower triglyceride levels and incidence of pancreatitis than those who received placebo. Finally, the discussion centres on the potential diagnostic criteria for access to plozasiran.

Support Statement

This course is supported by an unrestricted educational grant from Arrowhead Pharmaceuticals.

Disclosure

In compliance with EBAC guidelines, all speakers/chairpersons participating in this programme have disclosed or indicated potential conflicts of interest which might cause a bias in the presentations. The Organising Committee/Course Director is responsible for ensuring that all potential conflicts of interest relevant to the course are declared.

Terms & Conditions

Radcliffe Education requires contributors to our CME programmes to disclose any relevant financial relationships that have occurred within the past 12 months that could create a conflict of interest. These will be identified in the 'Faculty' section if applicable.

 

The course, ‘Advancements in Triglyceride-lowering Therapies: Insights from ESC 2024’, is accredited by the European Board for Accreditation of Continuing Education for Health Professionals (EBAC) for 1 hour of external CME credits.

 

Each participant should claim only those hours of credit that have actually been spent in the educational activity. EBAC works according to the quality standards of the European Accreditation Council for Continuing Medical Education (EACCME), which is an institution of the European Union of Medical Specialists (UEMS).

 

Through an agreement between the European Board for Accreditation in Cardiology and the American Medical Association, physicians may convert EBAC External CME credits to AMA PRA Category 1 Credits™. Information on the process to convert EBAC credit to AMA credit can be found on the AMA website. 

Instruction to Participants

There is no fee for taking part in this online learning activity.

 

Activities are designed to be completed within 60 minutes and must be completed by the registered user. Physicians should only claim credits for time spent on the activity. To successfully earn credit, participants must complete the activity in full in the indicated time frame.

 

To complete the course and claim certification participants must: 

  • Read the course outline information supplied. Users must read and study the activity in its entirety before completing the post-test questions. 
  • Your results will be automatically saved and if a pass score is achieved, you may be eligible to claim credit for the activity and receive a certificate of completion. 

Target Audience

  • Cardiologists
  • Endocrinologists
  • Primary care physicians
  • Lipidologists
  • Diabetologists

Learning Objectives

Upon completion of this activity, participants will be able to:

  • Recall the primary and secondary outcomes from key triglyceride-lowering trials presented during ESC 2024
  • Discuss the current and future implication of trial results to clinical management and practice guidelines

Module

Title

Duration

Speakers

Chapter 1 Severe Hypertriglyceridaemia: Pathophysiology and Practical Management 7m Gerald Watts Robert Rosenson
Chapter 2 Severe Hypertriglyceridaemia: Risk Factors and Risk Assessment 7m Gerald Watts Robert Rosenson
Chapter 3 Genetic and Phenotypic Basis of FCS 4m Gerald Watts Robert Rosenson
Chapter 4 New Data in FCS: PALISADE Results From ESC 2024 14m Gerald Watts Robert Rosenson
Chapter 5 PALISADE in Context: Implementation in the Real World 9m Gerald Watts Robert Rosenson
Chapter 1.

Severe Hypertriglyceridaemia: Pathophysiology and Practical Management

Duration: 7m

Speakers: Gerald Watts Robert Rosenson

Chapter 2.

Severe Hypertriglyceridaemia: Risk Factors and Risk Assessment

Duration: 7m

Speakers: Gerald Watts Robert Rosenson

Chapter 3.

Genetic and Phenotypic Basis of FCS

Duration: 4m

Speakers: Gerald Watts Robert Rosenson

Chapter 4.

New Data in FCS: PALISADE Results From ESC 2024

Duration: 14m

Speakers: Gerald Watts Robert Rosenson

Chapter 5.

PALISADE in Context: Implementation in the Real World

Duration: 9m

Speakers: Gerald Watts Robert Rosenson

Chair

Gerald Watts

Gerald Watts

University of Western Australia, Perth, Australia

Prof Gerald Watts is Chair of the Familial Hypercholesterolaemia Australasia Network and a Senior Consultant Physician specialising in cardio-metabolic medicine.

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Speaker

Robert Rosenson

Robert Rosenson

Mount Sinai Icahn School of Medicine, New York, US

Dr Robert Rosenson is a Professor of Medicine and Cardiology at the Icahn School of Medicine and the Director of Metabolism and Lipids for the Mount Sinai Health System.

View full profile
1.00 EBAC

Advancements in Triglyceride-lowering Therapies: Insights from ESC 2024 programme has been accredited by the European Board for Accreditation of Continuing Education for Health Professionals (EBAC) for 1 CME point, equating to 1 hour of learning. Physicians may convert EBAC External CME credits to AMA PRA Category 1 Credits™.

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